Dr. Roger Seheult of MedCram explains new research on Neu5Gc, a sialic acid molecule found in meat and dairy, and how it may contribute to severe COVID-19 symptoms, inflammation, and certain chronic diseases and cancers.

Roger Seheult, MD is the co-founder and lead professor at MedCram
He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

Interviewer: Kyle Allred, Physician Assistant, Producer, and Co-Founder of MedCram.com

This video was recorded on May 13, 2021

TOPICS IN THIS VIDEO INCLUDE:

00:00 Introduction to sialic acids and why they’re important
00:39 What are sialic acids?
01:53 Introduction to Neu5Ac (in humans) & Neu5Gc (in other mammals)
03:41 Why are Neu5Ac and Neu5Gc important?
05:41 Human antibodies against Neu5Gc-glycans, chronic inflammation, & xenosialitis
07:21 French NutriNet-Sante study and “Gcemic Index” of foods
08:40 Does just red meat contain Neu5Gc? What about poultry, eggs, & fish?
09:14 Neu5Gc intake differences in men & women
10:26 Association between BMI, plant-based diets, & sialic acids
13:02 Cycle of obesity & inflammation
13:30 Biologic therapy & coronary inflammation
14:51 Dr. Esselstyn’s work on diet & coronary artery disease
16:01 Risks of meat consumption – processed versus unprocessed
20:00 Health benefits of red meat consumption
22:01 Summary of diets & associated outcomes, looking ahead to COVIDENCE UK Study

LINKS / REFERENCES:

Mechanism of uptake and incorporation of the non-human sialic acid N-glycolylneuraminic acid into human cells (Journal of Biological Chemistry) | 

From “Serum Sickness” to “Xenosialitis”: Past, Present, and Future Significance of the Non-human Sialic Acid Neu5Gc (Frontiers in Immunology) | 

Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to cancer: French NutriNet-Santé study (BMC) | 

Adventist Health Study-2 (Loma Linda University Health) | 

Association of Biologic Therapy With Coronary Inflammation in Patients With Psoriasis as Assessed by Perivascular Fat Attenuation Index (JAMA) | 

A plant-based diet and coronary artery disease: a mandate for effective therapy (Journal of Geriatric Cardiology) | 

Meat consumption and risk of 25 common conditions: outcome-wide analyses in 475,000 men and women in the UK Biobank study (BMC) | 

The COVIDENCE UK Research Study has been developed in response to the outbreak of coronavirus disease (Queen Mary University of London) | 

All coronavirus updates are at MedCram.com (including more discussion on: does red meat cause cancer, cardiovascular disease, sialic acid, dairy and red meat cancer, COVID 19 Vaccines, and more).

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Video Produced by Kyle Allred

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#COVID19 #SialicAcid #Neu5Gc

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